Ipamorelin is a GHRP (growth hormone releasing peptide) receptor-active GH secretagogue, it doesn't significantly effect cortisol or prolactin, so this makes it highly specific for GH release.
Aib-His-D-2-Nal-DPhe-Lys-NH2
It has also been found that 12 weeks of treatment with ipamorelin increased bone mass in young adult female rats in one study that can be found on pubmed.
It is important to remember that Ipamorelin is a ghrelin mimetic, and an analog to ghrelin.
However it doesn't cause the kind of hunger feelings caused by ghrp-6.
Ipamorelin acts with synergy when used during your own GHRH (growth-hormone releasing hormone) pulse or when coadministered with GHRH or a GHRH analog such as Sermorelin or cjc.
The synergy comes about due to both the obvious suppression of Somatostatin and the increases in GH release per-somatotrope, while GHRH increases the number of somatotropes that release GH.
Due to the fact that its selective and doesn't really alter cortisol or prolactin levels, this makes Ipamorelin a very exciting peptide, it is as effective as ghrp-6 without the increase in hunger or cortisol or prolactin serum levels, and it has another property unique to Ipamorelin.
A mega-dose of Ipamorelin results in a mega-release of GH (up to the entire amount that is actually present in the pituitary), whereas GHRP-2 and GHRP-6 have limits of approximately 1mcg/kg in humans for their maximal GH release.
I find this very exciting when used directly after training to increase recovery and in the maturation of satellite muscle cells.
